Key Questions and Answers about Ibuprofen Use for COVID-19

If I am experiencing symptoms consistent with coronavirus, should I take ibuprofen?

With the most current information available, the World Health Organization (WHO) has stated they are not recommending against taking Ibuprofen. This means that you can still take ibuprofen to manage symptoms. Please refer to the diagram below for the WHO statement.


If I am experiencing symptoms consistent with coronavirus, should I take naproxen or other NSAIDs?

Yes, as long as you follow normal guidelines for daily intake of these medications. There has been no information that naproxen or other NSAIDs have an adverse impact with respect to COVID-19.


WHO Ibuprofen Announcement

These questions arose after a March 17th WHO announcement where they recommended against the use of ibuprofen (Motrin, Advil, among other brands) for patients with COVID-19 symptoms, due to a concern that anti-inflammatory drugs could worsen the COVID-19 infection. Likewise, acetaminophen (Tylenol, among other brands) is still safe to use as directed.  The theory hypothesized that ibuprofen could increase an enzyme, ACE2, that is used by the virus to infect the host. There is no evidence that other medications impacting that pathway, such as ACE inhibitors and ARBs, play any role in COVID-19 either.  Patients should continue to use prescribed medications as directed by their physicians.


For more information from WHO about COVID-19, visit


Posted March 20, 2020

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